Lenticule extraction (KLEx) is the manufacturer-neutral technical term for laser procedures in which a disc of tissue (lenticule) is cut inside the cornea and removed through a small opening. This family includes ReLEx SMILE and SMILE pro (Carl Zeiss Meditec), SmartSight (SCHWIND), CLEAR (Ziemer) and SILK (Johnson & Johnson).
What they all have in common: no flap is cut and folded back, the uppermost corneal layer remains intact apart from the small opening, and fewer corneal nerves are severed than with LASIK. In studies on SMILE, dry-eye symptoms were subjectively milder than after Femto-LASIK, while the objective measurements were similar (Shen 2016).





